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目的:调查分析上海地区2005年上半年抗菌药物使用情况,促进抗菌药物合理使用。方法:抽查上海地区20所二、三级医院抗菌药物管理制度、出院病历、门诊处方和使用情况。结果:抗菌药物收入总额占药品收入总额的比例为21．57—25．01％;使用率高达70％以上;头孢菌素类药物使用最多,接近于50％;病原学送检率和药敏试验率分别低于15％和9％;三级医院在平均处方金额上高出二级医院18．5％;住院病人抗菌药物DDDs以左氧氟沙星最高,各种头孢菌素类次之。结论:不合理使用抗菌药物导致医疗资源浪费的情况仍很普遍,各医院的监管力度还有待于进步加强。
Objective: To investigate and analyze the usage of antibacterials in Shanghai in the first half of 2005 and promote the rational use of antibacterials. Methods: A total of 20 secondary and tertiary hospitals in Shanghai area antibacterial drug management system, discharge records, outpatient prescriptions and usage. Results: The proportion of the total amount of antibacterial drugs in the total drug revenue was 21.57-25.01%; the rate of use was as high as 70%; the use of cephalosporins was the most, which was close to 50%; the rate of etiological examination and drug sensitivity The experimental rates were lower than 15% and 9% respectively. The average prescriptions of tertiary hospitals were 18.5% higher than those of secondary hospitals. The DDDs of inpatients with levofloxacin were the highest, followed by cephalosporins. Conclusion: The situation of irrigated use of antimicrobial agents to wastage of medical resources is still common, and the supervision of various hospitals needs further improvement.