尽管新的抗生素在不断开发和应用,而肺炎仍是主要的致死性疾病,近15年来其病死率未见大幅度变动。目前,细菌性肺炎大部分发生于恶性肿瘤晚期等免疫低下人群。本文根据虎门医院尸检结果对抗生素应用的变迁与肺炎之关系作一探讨。肺炎根据其炎症发生部位的不同可分为主要发生于肺泡内的局灶性肺炎(支气管肺炎)和发生于肺泡间隔的间质性肺炎二大类。主要由革兰氏阳性球菌或肠 Although new antibiotics are being continuously developed and applied, and pneumonia is still the leading fatal disease, there has been no significant change in the case fatality rate in the past 15 years. At present, the majority of bacterial pneumonia occurs in immunocompromised people in later stages of malignancy. This article based on the results of autopsy in Humen Hospital on the relationship between the changes of antibiotics and pneumonia for a discussion. Pneumonia according to its different parts of the inflammation can be divided into mainly occurs in the alveolar focal pneumonia (bronchial pneumonia) and occurred in the alveolar septum pneumonitis two categories. Mainly by Gram-positive cocci or intestinal