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本文报告130例新生儿化脓性脑膜炎(化脑),其中并发脑室炎15例,脑脓肿6例。脑脊液病原菌培养阳性18例,以大肠杆菌占多数。15例脑室炎,经脑室穿刺液而确诊,其中8例有头颅超声典型表现。6例脑脓肿中5例为头颅超声所证实,脓肿部位在额叶和顶叶;1例尸解发现为多发性脑脓肿伴肾脓肿。本文认为凡化脑起病急,临床症状严重者应及时进行头颅超声或CT检查,以便早期发现脑室炎及脑脓肿。
This article reports 130 cases of neonatal purulent meningitis (brain), of which 15 cases of concomitant ventricular inflammation, brain abscess in 6 cases. Cerebrospinal fluid pathogen culture positive in 18 cases, with E. coli accounted for the majority. 15 cases of ventricular inflammation, confirmed by intraventricular puncture fluid, of which 8 cases have a typical manifestation of head ultrasound. Five of the six cases of brain abscess were confirmed by cranial ultrasound. The abscesses were located in the frontal and parietal lobes. One case of autopsy found multiple brain abscess with renal abscess. This article thinks that all the sudden onset of brain disease, severe clinical symptoms should be timely head ultrasound or CT examination in order to early detection of intraventricular and brain abscess.