克山病的胰腺病变及其意义(摘要)

来源 :白求恩医科大学学报 | 被引量 : 0次 | 上传用户:qiuyucen
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复查了楚雄地区克山病尸检中能观察的胰腺切片92例,其中亚急克55例,慢克37例。为了对比,并复查了楚雄地区非克山病尸检中能观察的胰腺切片15例,本校病理解剖教研室连续尸检1008例中能观察的胰腺切片405例,和4400例尸检中非克山病性心脏病有能观察胰腺切片的99例,各种门脉回流受阻的病例37例。克山病除了常见间质性胰腺炎改变外,还常具有胰腺腺泡不同程度的萎缩性改变。胰腺腺泡萎缩有两型,我们分别称为腺样萎缩和隔状萎缩。腺样萎缩的腺泡有不同程度萎缩但仍保持腺样外观。在克山病,单纯的腺样萎缩很少见,胰腺的隔状萎缩在病理上有一定的特征性,萎缩的腺泡隔状分割胰腺小叶,残留腺泡集成结节状而通常胰岛不受累。克山病胰腺隔状萎缩的发生率高,楚雄地区92例克山病中,胰腺重度隔状萎缩的发生率达43.5%(40/92)。克山病的这些胰腺病变,有助于解释疾病过程中常见的消化道症 A total of 92 pancreatic sections that could be observed in the autopsy of Keshan disease in Chuxiong area were reviewed. Among them, 55 cases were subacute and 37 cases were slow-moving. For comparison, we reviewed 15 cases of pancreas slices that could be observed in the autopsy of non-Keshan disease in the Chuxiong area. The Department of Pathology and Anatomy of the University had 405 cases of pancreas sections that could be observed in 1008 consecutive autopsies, and 4400 cases of non-Keshan disease heart in autopsy. There were 99 cases with observable pancreas sections and 37 cases with various portal vein obstructions. In addition to the common changes in interstitial pancreatitis, Keshan disease often has varying degrees of atrophic changes in the pancreatic acini. There are two types of pancreatic acinar atrophy, we call it adenoid atrophy and septal atrophy. Adenoidal atrophic acini shrink to varying degrees but still maintain a glandular appearance. In Keshan disease, simple adenoid atrophy is rare, and the septal atrophy of the pancreas has certain characteristics in pathology. The atrophic acinar septately divides the pancreatic lobules, and the residual acinus is integrated into the nodular and usually the islets are not involved. . Keshan disease has a high incidence of pancreatic septal atrophy. Among 92 cases of Keshan disease in Chuxiong, the incidence of severe septal atrophy of the pancreas reached 43.5% (40/92). These pancreatic lesions of Keshan disease help explain common gastrointestinal diseases during the disease process
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