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目的 探讨肾综合征出血热 (HFRS)患者血清白细胞介素 - 8(IL - 8)的变化。方法 采用 Elis A法检测 39名 HFRS患者血清中 IL- 8水平。结果 HFRS患者 (出血热组 )血清 IL- 8水平均比健康人 (对照组 )升高 ,尤以少尿期为甚 (P<0 .0 0 1)。结论 血清 IL - 8水平对判断 HFRS患者的病情轻重有重要的临床价值。
Objective To investigate the changes of serum interleukin - 8 (IL - 8) in patients with hemorrhagic fever with renal syndrome (HFRS). Methods Elis A method was used to detect IL-8 levels in 39 HFRS patients. Results Serum levels of IL-8 in HFRS patients (hemorrhagic fever group) were significantly higher than those in healthy people (control group), especially in oliguria (P <0.01). Conclusion Serum IL - 8 levels have important clinical value in judging the severity of HFRS patients.