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目的 :观察灵杆菌素对肿瘤化疗后白细胞减少的治疗作用及不良反应。方法 :收集80例癌症患者临床资料 ,其中包括肺癌、非霍奇金淋巴瘤瘤、乳腺癌、头颈部癌、白血病等病种 ,随机分为灵杆菌素治疗组和惠尔血对照组 ,对比观察两组白细胞的变化及不良反应。结果 :两组治疗对化疗后白细胞减少的疗效无显著差异 ,灵杆菌素的不良反应主要为发热、骨骼肌肉疼痛、皮疹、局部硬结 ,患者均能耐受 ,与惠尔血的不良反应无明显差异。结论 :灵杆菌素对化疗后白细胞减少的治疗作用与惠尔血相似 ,毒性可耐受 ,价格便宜 ,值得推广应用
Objective: To observe the therapeutic effects and adverse reactions of schwannin on neutropenia after chemotherapy. METHODS: Clinical data of 80 patients with cancer were collected, including lung cancer, non-Hodgkin’s lymphoma, breast cancer, head and neck cancer, and leukemia. They were randomly divided into a treatment group and a blood control group. The changes of white blood cells and adverse reactions were observed in both groups. Results: There was no significant difference in the efficacy of leukopenia after chemotherapy between the two groups. The adverse reactions of schizophyllan were mainly fever, musculoskeletal pain, skin rash, and local induration. The patients were tolerated and the adverse reactions to Whirlpool blood were not obvious. difference. Conclusion: Therapeutic effect of schizophyllan on leukopenia after chemotherapy is similar to that of Whirlpool. Toxicity can be tolerated and the price is cheap. It is worth popularizing and applying.