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目的 Xpert MTB/RIF在肺结核病人痰菌阳性标本检测中的应用价值。方法 2015年10月~2016年9月我所收治肺结核痰菌阳性患者427例,分别进行Xpert MTB/RIF实验法、PNB生长实验、比例法药敏实验。结果Xpert MTB/RIF实验法与PNB生长实验培养、比例法药敏实验相比差异无统计学意义(P>0.05)。结论在结核病诊断中采用Xpert MTB/RIF法敏感性、特异性均较高,其能够快速判断分枝杆菌菌种及利福平耐药状况,临床医生可将其作为初治结核病痰菌阳性患者诊断首选方法。
Objective To investigate the value of Xpert MTB / RIF in the detection of sputum positive specimens from patients with pulmonary tuberculosis. Methods From October 2015 to September 2016, 427 cases of sputum positive pulmonary tuberculosis patients were treated by Xpert MTB / RIF, PNB, and drug sensitivity test. Results There was no significant difference between Xpert MTB / RIF test and PNB test (P> 0.05). Conclusion The sensitivity and specificity of Xpert MTB / RIF method in the diagnosis of tuberculosis are high, which can quickly determine the mycobacterial species and rifampicin resistance status, clinicians can be used as a first-out TB sputum positive patients The preferred method of diagnosis.