在病人和动物实验观察中都证明嗜热放线菌具有抗原性,可诱发体液和细胞介导的肺免疫反应。本病的发生与个体免疫状态有关,例如具有特应性(atopy) 素质者,接触抗原后,可触发哮喘样发作。无特应性者,接触抗原后,通过特异性抗体,形成免疫复合物,引起过敏性细支气管肺泡炎。此病以形成巨噬细 The thermophilic actinomycetems have been shown to be antigenic in both patient and animal experiments to elicit humoral and cell-mediated pulmonary immune responses. The occurrence of this disease and individual immune status, such as atopy quality, contact with antigen, can trigger an asthma-like attack. No atopy, contact with antigen, through specific antibodies, the formation of immune complexes, causing allergic bronchiolitis alveolitis. The disease to form macrophilia