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目的通过对汕头市病毒性脑炎的病原监测,了解该地区病毒性脑炎的病原谱及发病情况。方法哨点医院对2006-2008年就诊的疑似脑炎病例进行血液及脑脊液标本采集,运送至汕头市疾病预防控制中心,采用ELISA法对脑炎疑似标本进行乙脑病毒(JEV)IgM、单纯疱疹病毒(HSV)IgM、巨细胞病毒(CMV)IgM、科萨奇病毒(COXV)IgM、埃可病毒(ECHO)IgM、腺病毒(ADV)IgM 6种病毒抗体项目检测。结果监测期间共接收148例疑似脑炎病例,采集的标本总共检出病毒抗体阳性标本19份,病毒总阳性率为12.8%。其中JEV阳性2份;HSV阳性6份;CMV抗体阳性1份;ECHO抗体阳性1份;ADV抗体阳性7份;HSV和ADV抗体阳性1份;ECHO和ADV抗体阳性1份。结论汕头市病毒性脑炎病原以ADV和HSV阳性率较高,需加强此类病毒的防控。
Objective To understand the etiological spectrum and incidence of viral encephalitis in Shantou through the pathogen detection of viral encephalitis in Shantou. Methods Sentinel Hospital collected blood and cerebrospinal fluid samples from suspected encephalitis patients who were treated in 2006-2008 and sent them to Shantou Municipal Center for Disease Control and Prevention for the detection of JEV IgM, herpes simplex (HSV) IgM, cytomegalovirus (CMV) IgM, coxsackievirus (COXV) IgM, ECHO IgM, adenovirus (ADV) IgM 6 virus antibody test. Results A total of 148 cases of suspected encephalitis were received during the surveillance period. Totally 19 samples were positive for virus antibody. The total positive rate of virus was 12.8%. Among them, 2 were positive for JEV, 6 were HSV positive, 1 was positive for CMV antibody, 1 was positive for ECHO antibody, 7 were positive for ADV antibody, 1 was positive for HSV and ADV antibody, and 1 was positive for ECHO and ADV antibody. Conclusion The prevalence of viral encephalitis in Shantou City is high in ADV and HSV. The prevention and control of this virus should be strengthened.