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作者采用特异内皮素（ＥＴ）抗体，通过放射免疫分析法，检测了４０名健康人血浆ＥＴ水平．同时，对其中２０名分别持续观察了１５０ｍｉｎ内的６次空腹及试餐后（面食１５０ｇ，水１００ｍｌ）血浆ＥＴ水平的动态变化．结果表明：４０名健康人血浆ＥＴ含量均值为１１．５３±５．７８ｎｇ／Ｌ；男性为１３．１４±６．１２ｎｇ／Ｌ女性为１１．３８±５．８０ｎｇ／Ｌ（Ｐ＞０．０５）；大于３０岁年龄组为１２．８７±６．０６ｎｇ／Ｌ，小于３０岁年龄组为９．０６±４．７８ｎｇ／Ｌ（Ｐ＜０．０５）．空腹组血浆ＥＴ平均含量波动于１２．７５～１４．３１ｎｇ／Ｌ，试餐组波动于６．５３～１０．５５ｎｇ／Ｌ试餐组１５０ｍｉｎ内６次血浆ＥＴ水平均低于空腹组（Ｐ＜０．０５～０．０１）．提示进面食餐对ＥＴ的释放有抑制效应．作者认为，这种抑制效应对保护胃肠粘膜和帮助食物消化吸收具有重要的生理意义．
The authors used specific endothelin (ET) antibodies to detect plasma ET levels in 40 healthy individuals by radioimmunoassay. At the same time, the dynamic changes of plasma ET levels in sixteen fasting and postprandial meals (pasta 150g, water 100ml) within 150min were observed continuously for 20 of them respectively. The results showed that the average plasma ET level of 40 healthy people was 11.53 ± 5.78ng / L, that of males was 13.14 ± 6.12ng / L, and that of females was 11.38 ± 5.80ng / L (P> 0.05 ). The mean age was 12.87 ± 6.06ng / L in the group over 30 years old and 9.06 ± 4.78ng / L in the group under 30 years old (P <0.05). The mean plasma ET level in fasting group fluctuated from 12.75 to 14.31 ng / L, and the plasma ET levels in the test group fluctuated from 6.53 to 10.55 ng / L in 6 months in the test meal group (P < 0.05 ~ 0.01). Prompted into the meal on the release of ET inhibitory effect. The author believes that this inhibitory effect on the protection of gastrointestinal mucosa and help digestion and absorption of food has important physiological significance.