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原发性甲状旁腺机能亢进(简称甲旁亢)系由甲状旁腺腺瘤或增生组织分泌过多的甲状旁腺激素所引起的盐类代谢紊乱性疾病。本病诊断和处理均较困难。我们自1981年以来手术治疗7例(术前已确诊,其中大医3例,甘省医3例,医大三院1例)。本文仅就甲状旁腺腺瘤所致的甲旁亢加以讨论。临床资料本组男性1例,女性6例,年龄15～46岁。临床表现为肢体疼痛,行路困难及骨质疏松。其中2例病理性骨折;2例合并泌尿系结石。病程9个月至4年。7例均行甲状旁腺腺瘤切除术,术中发现腺瘤位于甲状腺左叶上极者3例,左叶下极者1例,位于右叶下极者3例。腺瘤小者2×1.5×1.5cm,大者达4.5×2.0×1.4cm,其颜色为棕黄色。术后均经病理证实。本组合并有甲状腺腺瘤者3例,术中一并切除。治疗结果:6例疗效满意,症状明显减轻或消失。随访2～3年血清钙磷恢复正常,X线检查骨密度增加,囊状透亮区消失,病理性骨折愈合,恢复工作。1例术后关节疼痛无减轻,但血钙磷测定在正常
Primary hyperparathyroidism (abbreviated as hyperparathyroidism) is a disorder of salt metabolic disorder caused by parathyroid hormone that is excessively secreted by parathyroid adenomas or hyperplastic tissues. Diagnosis and treatment of this disease are more difficult. We have had surgical treatment in 7 cases since 1981 (have been diagnosed before surgery, including 3 major doctors, 3 provincial doctors, and 1 junior medical college). This article only discusses parathyroid paralysis caused by parathyroid adenomas. The clinical data of this group were 1 male and 6 female, aged 15-46 years. Clinical manifestations are limb pain, difficulty in walking and osteoporosis. Two of them were pathological fractures; two were complicated with urinary stones. Duration of 9 months to 4 years. Resection of parathyroid adenoma was performed in 7 cases. The adenoma was found in 3 cases of the left upper lobe of the thyroid, 1 case of the left lower lobe, and 3 cases of the right lower lobe. The small adenomas were 2 x 1.5 x 1.5 cm, and the majority were 4.5 x 2.0 x 1.4 cm. Their color was brown-yellow. All cases were confirmed by pathology. The combination of thyroid adenoma in 3 cases, the surgery was removed. Treatment results: 6 cases of satisfactory results, symptoms significantly reduced or disappeared. Followed up for 2 to 3 years, serum calcium and phosphorus returned to normal, bone density increased with X-ray examination, cystic translucent area disappeared, pathological fractures healed, and work resumed. One case had no relief of joint pain, but serum calcium and phosphorus were normal.