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目的:研究卡铂(CBP)联合口服足叶乙苷胶囊(威克)方案在老年晚期肺癌中的应用。方法:将41例年龄大于70岁的肺癌患者随机分为两组,治疗组患者接受CBP+威克方案化疗,对照组接受对症及支持治疗。结果:治疗组患者生活质量及近期有效率均高于对照组患者,且差异有显著性(P<0.05)。结论:老年晚期肺癌患者可适当给以化疗,以提高患者的生存质量及生存期。
Objective: To study the application of carboplatin (CBP) combined with oral etoposide capsule (Wick) in elderly patients with advanced lung cancer. Methods: Forty-one patients with lung cancer older than 70 years old were randomly divided into two groups. Patients in the treatment group received CBP plus Wacker Chemotherapy and patients in the control group received symptomatic and supportive care. Results: The quality of life and the recent effective rate in the treatment group were higher than those in the control group, and the difference was significant (P <0.05). Conclusion: Elderly patients with advanced lung cancer may be given appropriate chemotherapy to improve the quality of life and survival of patients.