单纯疱疹病毒性脑炎(HSE)是一种急性坏死性脑炎,由Ⅰ型或Ⅱ型单纯疱疹病毒(HSV)感染引起,死亡率高达70％,仅10％的病人可恢复正常生活能力。国外统计资料显示HSE约占全部脑炎的5％～20％,占已知病毒性脑炎的20％～68％。我国北京地区统计占“散发性脑炎”的18％。自从无环鸟苷应用于临床后,HSE的预后有了很大改善。研究认为无环鸟苷的疗效与用药早晚有很大关系,越早应用,疗效越好。因此 Herpes simplex encephalitis (HSE) is an acute necrotizing encephalitis that causes as high as 70% mortality from herpes simplex virus type 1 or herpes simplex virus type 2 (HSV) infection and returns to normal viability in only 10% of patients. Foreign statistics show that HSE accounts for about 5% ~ 20% of all encephalitis, accounting for 20% ~ 68% of known viral encephalitis. Statistics of Beijing in our country account for 18% of “sporadic encephalitis.” Since acyclovir is used clinically, the prognosis of HSE has been greatly improved. Studies suggest that acyclovir efficacy and medication sooner or later have a great relationship, the sooner the application, the better the effect. therefore