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丙胺苯丙酮的临床药理学本品是一种较新的抗心律失常药。它有广谱,效好,易于耐受的特点。兹就药理学方面讨论如下: 一、药代动力学:口服95％被吸收,由于肝脏的首过效应,仅5～12％进入全身。服药后2—3小时可达最高血浆浓度,随着用药量的增加,血值呈倍数增加,水剂较片剂的利用率高,其97％与蛋白结合。肺内浓度最高,比心、肝高10倍,比肌肉及肾高20
Prophylactin propiophenate clinical pharmacology This product is a newer anti-arrhythmic drug. It has broad spectrum, effective, easy to tolerate characteristics. Pharmacological aspects are as follows: First, pharmacokinetics: 95% oral absorption, due to the first pass of the liver effect, only 5 to 12% into the body. Up to 2-3 hours after taking the drug up to the highest plasma concentration, with the increase in the amount of medication, the blood was a multiple of increase, the utilization of water-based tablets than high, 97% of its protein binding. The highest concentration in the lungs, heart, liver 10 times higher than the muscle and kidney 20