目的 :研究脊髓亚急性联合变性 ( SCD)的病因 ,临床特征和辅助检查。方法 :对三年来我院收治的 14例 SCD病例进行综合分析。结果 :除血清维生素 B12缺乏外 ,慢性胃炎、食道、十二指肠憩息 ,胃切除术后是其主要原因。肢体感觉异常是最常见的首发症状 ,脊髓损害以后索和锥体束为主。结论 :SCD是一种可治性疾病 ,早期诊断、早期治疗对预后起着决定性作用 Objective: To study the etiology, clinical features and auxiliary examinations of spinal cord subacute combined degeneration (SCD). Methods: A total of 14 cases of SCD treated in our hospital over the past three years were analyzed comprehensively. Results: In addition to serum vitamin B12 deficiency, chronic gastritis, esophagus, duodenum rest, gastrectomy is the main reason. Abnormal limb sensation is the most common initial symptom of spinal cord injury and pyramidal tract after the main beam. Conclusion: SCD is a treatable disease. Early diagnosis and early treatment play a decisive role in prognosis