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采用双抗体夹心ELISA法对56例食管鳞癌患者血清可溶性白细胞介素2受体(SIL—2R)水平进行了测定。结果发现食管鳞癌患者血清SIL—2R水平显著高于正常对照组(P<0.05),并与临床分期有关;手术后患者血清SIL—2R水平较术前明显下降(P<0.05)。结果提示患者血清SIL—2R检测对食管癌的辅助诊断具有重要价值,且有助于患者预后的判断。
The serum levels of soluble interleukin 2 receptor (SIL-2R) in 56 patients with esophageal squamous cell carcinoma were measured by double antibody sandwich ELISA. The results showed that serum SIL-2R levels in patients with esophageal squamous cell carcinoma were significantly higher than those in the normal control group (P<0.05), and were related to clinical stage; serum SIL-2R levels after surgery were significantly lower than before surgery (P<0.05). The results suggest that the detection of serum SIL-2R in patients has important value in the diagnosis of esophageal cancer and contributes to the prognosis of patients.