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目的:观察帕金森病合并糖尿病患者的非运动症状情况。方法:选择我院神经内科帕金森病100例,根据是否合并糖尿病分为观察组和对照组各50例,采用非运动症状评价量表(NMSS)进行非运动症状评估,观察两组患者非运动症状发生频率、非运动症状评分,以及非运动症状与临床变量的相关关系。结果:观察组胃肠道症状、泌尿系统病症、性功能阳性率显著高于对照组(P<0.05);观察组非运动症状评分(18.60±4.60)分,显著高于对照组的(16.85±4.52)分(P<0.05);两组非运动症状阳性率、评分与病程、H-Y分级呈非常显著正相关(P<0.01)。结论:合并糖尿病的帕金森患者非运动症状阳性率、严重程度均有所增加。
Objective: To observe the non-motor symptoms of Parkinson’s disease with diabetes. Methods: One hundred patients with Parkinson’s disease in our department were divided into observation group and control group according to whether they had diabetes mellitus or not, and non-exercise symptoms were evaluated by NMSS. Symptom frequency, non-motor symptom score, and non-motor symptoms and clinical variables. Results: The positive rates of gastrointestinal symptoms, urinary system disorders and sexual functions in the observation group were significantly higher than those in the control group (P <0.05). The score of non-motor symptom (18.60 ± 4.60) in the observation group was significantly higher than that in the control group (16.85 ± 4.52) (P <0.05). There was a significant positive correlation between the positive rate of non-motor symptoms and the course of disease and HY classification (P <0.01). Conclusion: The positive rate and severity of non-motor symptoms in patients with Parkinson’s disease with diabetes mellitus have increased.