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为了开展肝移植,我院自1973年起有计划地系统地施行了狗的原位肝移植术130例。几经改进术式,定型手术98次,其中狗清醒21条,最长存活65小时,能咬物、饮水、站立、行走和奔跑。取得了较多有益的经验和有用的教训后,于1977年开始,应用于临床,共2例,受者均为原发性肝癌患者。第一例存活6天,第二例术后肝功能恢复较好,存活93天,存活期间一般情况良好,食欲、睡眠正常,术后56天开始下床活动。先后经受了6次急性排斥反应,死于曲菌性败血症。
In order to carry out liver transplantation, our hospital systematically implemented 130 cases of orthotopic liver transplantation in dogs since 1973. After several improvements in surgery, stereotyped surgery 98 times, of which dogs awake 21, the longest survival of 65 hours, to bite, drink, stand, walk and run. Obtained more useful experience and useful lessons, beginning in 1977, applied to clinical, a total of 2 cases, the recipients are patients with primary liver cancer. The first case of survival of 6 days, the second case of good recovery of liver function, survival of 93 days, the general survival during the good appetite, sleep normal, 56 days after the onset of bed activity. Has undergone 6 acute rejection, died of aspergillosis sepsis.