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目的研究胃全切除手术和胃部分切除手术对胃癌患者预后的影响。方法 115例胃癌手术的患者,根据手术方式分为对照组(55例)和观察组(60例)。对照组患者采用胃全切除手术治疗,观察组患者采用胃部分切除手术治疗。比较两组患者在术后的肛门排气时间、下床活动时间、住院时间、血清白蛋白水平、CD4+/CD8+比值以及并发症发生情况。结果观察组胃癌患者的肛门排气时间为(2.35±1.56)d、下床活动时间为(1.48±0.91)d、住院时间为(7.68±2.89)d,对照组患者的肛门排气时间(3.47±1.86)d、下床活动时间(2.64±1.45)d,住院时间(10.49±3.14)d,观察组患者肛门排气时间、下床活动时间、住院时间均短于对照组(P<0.05)。观察组患者的血清白蛋白、CD4+/CD8+比值分别为(33.91±2.41)g/L、(1.69±0.26)%,明显优于对照组患者的血清白蛋白(38.15±2.48)g/L、CD4+/CD8+比值(1.19±0.32)%,差异具有统计学意义(P<0.05)。观察组患者术后并发症发生率为5.00%;对照组患者为18.18%,观察组术后并发症发生率明显低于对照组(P<0.05)。结论与胃全切除手术相比,胃部分切除手术能大大降低手术对患者的损伤,减少发生并发症的风险,提高患者的预后水平。
Objective To study the effect of total gastrectomy and partial gastrectomy on the prognosis of patients with gastric cancer. Methods One hundred and fifteen patients with gastric cancer were divided into control group (55 cases) and observation group (60 cases) according to the operation method. Patients in the control group were treated with total gastrectomy, while patients in the observation group were treated with partial gastrectomy. The time of anus exhaust, ambulation time, hospital stay, serum albumin, CD4 + / CD8 + ratio and complication were compared between the two groups. Results The anal exhaust time was (2.35 ± 1.56) d in gastric cancer patients in observation group, (1.48 ± 0.91) d in ambulation time, and (7.68 ± 2.89) days in hospital stay. The anal exhaust time in the control group (3.47 ± 1.86 d, ambulation time (2.64 ± 1.45) d and hospital stay (10.49 ± 3.14) d. The anal exhaust time, ambulation time and hospital stay in the observation group were shorter than those in the control group (P <0.05) . Serum albumin and CD4 + / CD8 + ratio in the observation group were (33.91 ± 2.41) g / L and (1.69 ± 0.26)% respectively, significantly higher than those in the control group (38.15 ± 2.48) g / L and CD4 + / CD8 + ratio (1.19 ± 0.32)%, the difference was statistically significant (P <0.05). The incidence of postoperative complications in the observation group was 5.00%; in the control group, 18.18%. The incidence of postoperative complications in the observation group was significantly lower than that in the control group (P <0.05). Conclusion Compared with total resection of the stomach, partial resection of the stomach can greatly reduce the operation of the patient’s injury, reduce the risk of complications and improve the prognosis of patients.