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目的探讨前列腺癌(PCa)和前列腺增生(BPH)患者膀胱内前列腺突入(IPP)长度差异对前列腺穿刺活检诊断的价值。方法 71例前列腺穿刺活检患者,均在经直肠超声(TRUS)引导下行自动活检枪前列腺穿刺活检,并经病理证实;同时测量IPP长度和前列腺体积(PV)。比较PCa组(22例)和BPH组(49例)IPP差异,分析IPP在不同截点水平诊断PCa的敏感度和特异度。结果 71例患者的IPP长度均值为(9.3±7.3)mm,PCa组为(6.6±5.0)mm,明显短于BPH组的(11.5±8.4)mm(P<0.05);IPP长度和PV呈显著正相关(r=0.691,P<0.05)。取IPP长度7.5mm作为截点值时,其判断PCa的特异度与灵敏度均为66.7%。结论 IPP是判断前列腺穿刺活检患者是否患PCa的一个有意义的指标;在IPP≤7.5mm的前列腺穿刺患者中,PCa检出率较高。
Objective To investigate the value of intrauterine prostatic protrusion (IPP) length difference between prostate cancer (PCa) and benign prostatic hyperplasia (BPH) in the diagnosis of prostatic biopsy. Methods Totally 71 prostatic biopsy patients underwent transrectal biopsy by direct transrectal ultrasound (TRUS), and confirmed by pathology. The length of IPP and the volume of the prostate (PV) were also measured. IPP differences between PCa group (n = 22) and BPH group (n = 49) were compared. The sensitivity and specificity of IPP in diagnosing PCa at different intercept levels were analyzed. Results The IPP length of 71 patients was (9.3 ± 7.3) mm, (6.6 ± 5.0) mm in PCa group was significantly shorter than that in BPH group (11.5 ± 8.4) mm (P <0.05). The length of IPP and PV were significant Positive correlation (r = 0.691, P <0.05). Take IPP length of 7.5mm as the cut-off value, the judge PCa specificity and sensitivity were 66.7%. Conclusions IPP is a meaningful indicator of PCa in patients with prostatic biopsy. The detection rate of PCa is higher in prostatic puncture patients with IPP≤7.5mm.