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本项研究应用脉冲多普勒技术测定正常人和器质性心脏病（冠心病、高心病、房颤）患者二尖瓣口及瓣下１、２、３ｃｍ处心室内不同部位的舒张早期充盈速度（Ｅ_０、Ｅ_１、Ｅ_２、Ｅ_３），并分别算出各点速度与瓣口速度的比值（Ｅ_１／Ｅ_０，Ｅ_２／Ｅ_０，Ｅ_２／Ｅ_０）。发现正常人上述各点速度和比值均无显著统计学差异，而器质性心脏病组一般Ｅ_２即开始降低，Ｅ_３显著降低，Ｅ_３／Ｅ_０与自身Ｅ_０／Ｅ_０、Ｅ_２／Ｅ_０相比有显著差异（心室内减射现象），而且各组Ｅ_３／Ｅ_０比值与常规测定舒张功能的指Ｅ／Ａ法之间存在良好的相关性。作者认为Ｅ_３／Ｅ_０比值是反映心室舒张功能障碍的良好指标，可以弥补Ｅ／Ａ法的不足之处。
In this study, pulsed Doppler echocardiography was used to measure the early diastolic filling in different parts of the heart and the mitral valve in patients with normal heart disease and organic heart disease (coronary heart disease, high heart disease, atrial fibrillation) (E_0, E_1, E_2, E_3) were calculated and the ratio of the velocities of each point to the velocities of the valve orifice were calculated (E_1 / E_0, E_2 / E_0, E_2 / E_0). There was no significant difference in the speed and the ratio of the above points in normal subjects, while the E_2 of EH group began to decrease and E_3 decreased significantly. E_3 / E_0 was significantly different from E_0 / E_0 and E_2 / E_0 (Intraventricular hypodermic phenomenon), and there was a good correlation between E_3 / E_0 ratio and the E / A method of routine measurement of diastolic function. The authors believe that E_3 / E_0 ratio is a good indicator of ventricular diastolic dysfunction, can make up for the shortcomings of the E / A method.