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目的探讨高海拔地区失血性休克早期限制性液体复苏的临床意义。方法2001年12月至2003年12月根据不同的复苏方式将41例失血性休克病人分为对照组和实验组,检测血红蛋白(HB)、血小板计数(PLT)、红细胞压积(HCT)、血清乳酸水平和失血量变化情况,比较限制性液体复苏与常规液体复苏对高海拔地区失血性休克病人的疗效。结果不同处置后12h两组HCT变化差异有显著性意义(P<0.05);12h及24h两组PLT变化差异有显著性意义(P<0.05);24h两组血清乳酸变化差异有显著性意义(P<0.05)。结论高海拔地区失血性休克病人早期液体复苏时,限制液体复苏相对于快速大量液体复苏不至于扰乱机体的代偿机制和内环境,且对改善细胞氧代谢更有利。
Objective To investigate the clinical significance of early limited fluid resuscitation in hemorrhagic shock at high altitude. Methods From December 2001 to December 2003, 41 patients with hemorrhagic shock were divided into control group and experimental group according to different recovery methods. The levels of hemoglobin (HB), platelet count (PLT), hematocrit (HCT), serum Lactate levels and changes in blood loss, and compare the efficacy of limited liquid resuscitation and conventional liquid resuscitation in hemorrhagic shock patients at high altitude. Results The changes of HCT in both groups at 12h after treatment were significantly different (P <0.05). The changes of PLT in 12h and 24h groups were significantly different (P <0.05). There was significant difference of serum lactic acid between the two groups P <0.05). Conclusion In the early stage of liquid resuscitation in hemorrhagic shock patients at high altitude, liquid resuscitation compared with rapid liquid resuscitation does not disturb the compensatory mechanism and internal environment of the body and is more beneficial to improve cell oxygen metabolism.