肿瘤的发生、发展与个体免疫力低下密切相关。为从流行病学方面验证这点,我们将原发性免疫不全作为宿主因素,用全国注册的原发性免疫不全综合征病人的资料,调查这些患者发生恶性肿瘤的情况。从1975年到1986年12月,全国注册的原发性免疫不全综合征病人男512例,女215例,共727例。其中78例初诊时为成人,其它均为小儿。患者类型依次为常见多样性免疫缺陷病(112例)、慢性肉芽肿症(93例)、选择性缺损(81例)、小儿伴性无r球蛋白血症(72例)、 The occurrence and development of tumors are closely related to the low immunity of individuals. To verify this from an epidemiological point of view, we used primary immunodeficiency as a host factor and investigated the incidence of these malignancies in patients with idiopathic immunodeficiency syndrome registered nationwide. From 1975 to December 1986, there were 512 males and 215 females with a total of 727 patients registered with primary immunodeficiency syndrome in China. Of these, 78 were newly diagnosed adults and others were children. The patient types were as follows: common immunodeficiency disease (112 cases), chronic granulomatous disease (93 cases), selective defect (81 cases), pediatric noncoprotein (72 cases)