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通过高效液相色谱及生物定性法观察了消炎病对致敏豚鼠肺在抗原攻击后释放白三烯的影响，致敏豚鼠肺组织剪成碎块分成两组：对照组：不含消炎痛；实验组：含消炎痛（8．4×10－6M）。用抗原激发过敏反应，肺组织过滤波进行生物定性及高效液相色谱测定。结果抗原激发致敏肺组织可释放出白三烯，白三烯含量消炎痛组：2956±955pmol／克肺；对照组：683±300pmol／克肺。两组差异有显著性意义（P＜0.01）。结果表明消炎痛处理后的豚鼠肺对抗原攻击后的反应增强是通过增加肺组织白三烯释放而实现的。
The effects of anti-inflammatory disease on the release of leukotrienes from the lungs of sensitized guinea pigs after antigen challenge were observed by high performance liquid chromatography and bioassay. The lungs of sensitized guinea pigs were cut into pieces and divided into two groups: control group: without indomethacin; Experimental group: containing indomethacin (8.4 × 10-6M). Antigen-induced allergic reactions, lung tissue filter biological qualitative and high performance liquid chromatography determination. Results Antigen stimulation sensitized lung tissue can release leukotriene, leukotriene indomethacin group: 2956 ± 955pmol / g lung; control group: 683 ± 300pmol / g lung. There was significant difference between the two groups (P <0.01). The results show that the increased response of anti-inflammatory guinea pigs to post challenge challenge is achieved by increasing leukotriene release.