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目的:研究冠心病并发焦虑症患者同时接受小剂量抗焦虑药物治疗对冠心病治疗的影响。方法:40例冠心病并发焦虑症患者随机分成试药组和常规组,试药组在常规组基础上加用小剂量抗焦虑药物治疗,用药4周后分别比较临床心绞痛发作次数,心电图改善程度,以及焦虑症状评定。结果:两组患者同等劳动程度心绞痛发作次数均明显减少,试药组总有效率为96%,常规组总有效率为79%,差异有显著性(P<0.05)。两组心电图总有效率(试药组84%,常规组85%)比较差异无统计学意义,两组治疗后SAS分数均有下降,但常规组差异无统计学意义,试药组SAS分数显著下降(P<0.05),差异有统计学意义,评分亦明显低于常规组(P<0.05),提示试药组的焦虑症状较常规组明显改善。结论:加用小剂量抗焦虑药物,在同等劳动程度下心绞痛发作次数明显减少,患者的焦虑症状也得到有效改善。
Objective: To study the effect of low-dose anxiolytic therapy on coronary heart disease in patients with coronary heart disease and anxiety. Methods: Forty patients with coronary heart disease complicated with anxiety were randomly divided into trial group and conventional group. The trial group was treated with low-dose anxiolytic drugs on the basis of conventional group. After 4 weeks of treatment, the number of clinical angina pectoris, the degree of improvement of electrocardiogram , And assessment of anxiety symptoms. Results: The incidences of angina pectoris in both groups were significantly reduced in both groups. The total effective rate was 96% in the test group and 79% in the conventional group, with significant difference (P <0.05). The total effective rate of two groups of ECG (84% in the test group, 85% of the conventional group) was no significant difference between the two groups SAS scores decreased after treatment, but the conventional group was no significant difference SAS group scores were significant (P <0.05). The difference was statistically significant and the score was also significantly lower than that of the conventional group (P <0.05), suggesting that the anxiety symptoms in the test group were significantly improved compared with the conventional group. Conclusions: With a small dose of anti-anxiety drugs, the number of angina pectoris significantly decreased under the same labor level, and patients’ anxiety symptoms have also been effectively improved.