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目的探讨高血压急症患者血脂、血清hsCRP、oxLDL水平及踝臂指数的变化。方法入选高血压患者120例,其中高血压急症79例,稳定高血压病41例。检测所有患者踝臂指数,同时测定血浆hsCRP、血尿酸、血纤维蛋白原、氧化低密度脂蛋白和血脂水平。结果与稳定性高血压组比较,高血压急症组ABI降低,差异有显著性(P<0.05);TC、LDL、oxLDL及hsCRP水平明显升高,差异有显著性(P<0.05)。结论高血压急症患者可能有更高的动脉僵硬度、炎症及氧化应激水平。
Objective To investigate the changes of serum lipids, serum hsCRP, oxLDL and ankle brachial index in patients with essential hypertension. Methods A total of 120 patients with hypertension were enrolled. Among them, 79 were hypertensive emergency and 41 were stable hypertension. The ankle-brachial index of all patients was measured. Plasma hsCRP, serum uric acid, fibrinogen, oxidized low density lipoprotein and blood lipids were also measured. Results Compared with stable hypertension group, the ABI in acute hypertension group was significantly lower than that in stable hypertension group (P <0.05). The levels of TC, LDL, oxLDL and hsCRP were significantly increased (P <0.05). Conclusion Patients with hypertension may have higher arterial stiffness, inflammation and oxidative stress.