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负压吸引是早妊人流的一种简单、相对安全的方法,但必需机械扩张宫颈,因此可以造成宫颈损伤尤其对于未产妇的人流。天然前列腺素(PGS)有扩张宫颈作用,但胃肠道副反应发生率高,且所需用药时间较长,因此临床应用价值不高。各种PG衍生物可降低其副作用并缩短用药时间,从而能在门诊进行合法的人流。本研究是用双盲法对40名未产妇在负压吸引人流前3小时阴道内放置含Meteneprost 10mg的阴道栓的宫颈扩张作用进行研究。Meteneprost是合成的PG衍生物(9-脱氧-16、16-双甲基-9甲撑PGE_2)。研究包括40名健康,孕3个月以内要求人流的未产妇,随机分为二组,每组20例,二组年龄和孕龄相似(年龄分别为21.8±
Vacuum suction is a simple, relatively safe method of early pregnancy flow, but it is necessary to mechanically expand the cervix, thus causing cervical lesions, especially for the uninvited persons. Natural prostaglandin (PGS) has an expanding cervical function, but the incidence of gastrointestinal side effects is high, and the required medication for a long time, so the clinical value is not high. Various PG derivatives reduce their side effects and shorten the duration of medication, allowing them to legitimately flow in clinics. This study was designed to investigate the cervical dilatation of 40 non-mothers with vaginal suppositories containing Meneprost 10 mg intravaginally in the vagina 3 hours prior to negative pressure-induced abortion by double-blind method. Meteneprost is a synthetic PG derivative (9-deoxy-16,16-bismethyl-9-methylene PGE 2). The study included 40 healthy pregnant women within 3 months of requiring abortion and were randomly divided into two groups of 20 patients each with similar age and gestational age (21.8 ±