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目的:总结多脏器功能障碍综合征(MODS)防治经验,以降低发病率及病死率。方法:选择1996年6月、1999年5月在ICU住院的50例患者,对其病因、临床表现、实验检查结果、监测参数、治疗方法及结果进行归纳统计。结果:肺受累40例,百分比为80％,且是MODS中首先受累器管,胃肠、肝。肾、心血管、中枢神经系统。血液系统呈序贯发生;各种治疗方法中,大黄对胃肠衰竭疗效较满意;2、3、4个脏器功能障碍病死率分别是25％、66％、83.3％,大于或等于5个脏器功能障碍病死率为100％,APACHE评分>20,MODS严重分期评分>9分者病死率较高。结论:多种原因可诱发MODS;治疗MODS方法是综合性,大黄对防治胃肠功能障碍有重要作用;对有诱发MODS原因者,宜尽早加强系统监测,尤其应警惕肺功能障碍的出现;MODS总病死率仍然较高。
Objective: To summarize the prevention and treatment of multiple organ dysfunction syndrome (MODS) to reduce the morbidity and mortality. Methods: Fifty patients hospitalized in ICU from June 1996 to May 1999 were selected and the etiology, clinical manifestations, laboratory test results, monitoring parameters, treatment methods and results were summarized. Results: 40 cases of lung involvement, the percentage of 80%, and is the first MODS in the affected tube, gastrointestinal, liver. Kidney, cardiovascular, central nervous system. The blood system was in a sequential pattern. Among various treatment methods, rhubarb was more satisfactory for the treatment of gastrointestinal failure; the mortality rates of 2,3,4 organ dysfunction were 25%, 66% and 83.3%, respectively, greater than or equal to 5 Organ dysfunction mortality was 100%, APACHE score> 20, MODS severe stage score> 9 points higher mortality. Conclusion: MODS can be induced by a variety of factors. The treatment of MODS is comprehensive. Rhubarb plays an important role in the prevention and treatment of gastrointestinal dysfunction. For patients with MODS, systematic monitoring should be strengthened as soon as possible, especially for the occurrence of pulmonary dysfunction. MODS The overall case fatality rate is still high.