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目的观察重症急性胰腺炎早期行肠内营养的临床疗效。方法 48例急性胰腺炎患者为研究对象,随机分为对照组和观察组,各24例,对照组在综合治疗基础上给予全胃肠外营养治疗,观察组在综合治疗基础上给予早期肠内营养治疗,比较两组治疗后疗效。结果两组治疗2周后,血清前白蛋白(PA)、白蛋白(ALB)较治疗前有明显升高,血红蛋白(Hb)及C-反应蛋白(CRP)明显降低,且观察组各指标改善程度均显著优于对照组(P<0.05);观察组平均住院时间短于对照组,感染、多器官功能失调综合征(MODS)发生率显著均低于对照组(P<0.05)。结论重症急性胰腺炎早期行肠内营养可有效改善患者的营养状况,减少感染、MODS等并发症的发生和促进康复,值得推广应用。
Objective To observe the clinical effect of early enteral nutrition in severe acute pancreatitis. Methods Forty-eight patients with acute pancreatitis were randomly divided into control group and observation group, 24 cases in each group. The control group received total parenteral nutrition treatment on the basis of comprehensive treatment. The observation group was given early enteral Nutritional therapy, the efficacy of the two groups after treatment was compared. Results After 2 weeks of treatment, serum prealbumin (ALB) and albumin (ALB) were significantly increased, hemoglobin (Hb) and C-reactive protein (CRP) were significantly decreased, and the indicators in the observation group were improved (P <0.05). The average length of stay in the observation group was shorter than that of the control group. The incidence of infection and multiple organ dysfunction syndrome (MODS) was significantly lower than that of the control group (P <0.05). Conclusion Early enteral nutrition in severe acute pancreatitis can effectively improve the nutritional status of patients, reduce the incidence of complications such as infection and MODS and promote rehabilitation, which is worth popularizing and applying.