用印度Ｔｏｒｒｅｎｔ公司所生产的罗红霉素治疗细菌性感染共６０例，进行开放性临床试验。罗红霉素剂量为１５０ｍｇ，每日２次，疗程７～１４ｄ。结果总有效率为９１．７％（５５／６０），其中呼吸道感染、泌尿生殖道感染、皮肤软组织感染有效率各为９１．４％、９１．７％和１００％。细菌清除率为８８％。４例（６．７％）有轻度不良反应，其中１例为轻度皮疹，３例为胃肠道反应。本研究证明罗红霉素有较好的临床效果，可用以治疗敏感菌引起的轻、中度感染 A total of 60 cases of bacterial infections were treated with roxithromycin produced by Torrent Corporation in India for an open clinical trial. Roxithromycin dose of 150mg, 2 times a day, treatment 7 ~ 14d. Results The total effective rate was 91.7% (55/60). The effective rates of respiratory infection, genitourinary tract infection and skin and soft tissue infections were 91.4%, 91.7% and 100% respectively. Bacterial clearance was 88%. Four patients (6.7%) had mild adverse reactions, including 1 mild rash and 3 gastrointestinal reactions. This study shows that roxithromycin has a good clinical effect, can be used to treat sensitive light-induced mild to moderate infection