论文部分内容阅读
目的:对比管状胃代食管术与全胃代食管术治疗食管癌的安全性与有效性。方法:2005年1月到2015年2月选择我院收治的100例食管癌患者,根据随机数字表法分为治疗组与对照组各50例,所有患者都行食管癌切除术,同时对照组给予全胃代食管手术,治疗组给予管状胃代食管术,对两组患者围手术指标、并发症及生活质量状况进行观察比较。结果:所有患者完成手术,治疗组的手术时间、术中出血量、术后住院时间、术后胃肠减压时间及术后闭式引流时间都明显少于对照组(P<0.05)。治疗组术后3个月反流性食管炎、胃排空障碍、胸胃综合征、吻合口狭窄、吻合口瘘等并发症发生情况明显少于对照组(P<0.05),日常生活、一般状况、治疗相关症状、社会影响、情感活动评分都明显高于对照组(P<0.05)。结论:相对于全胃代食管术,管状胃代食管术在治疗食管癌患者中的应用具有更好的安全性与有效性,值得进一步临床研究与推广。
Objective: To compare the safety and efficacy of tubular gastric esophageal esophageal surgery and total esophageal esophagectomy in the treatment of esophageal cancer. Methods: From January 2005 to February 2015, 100 patients with esophageal cancer admitted to our hospital were selected and randomly divided into treatment group (50 cases) and control group (50 cases). All patients underwent esophageal resection and the control group All patients were given esophageal surgery, and the treatment group was given tube-shaped gastric esophageal surgery. Perioperative indexes, complications and quality of life of the two groups were observed and compared. Results: The operation time, intraoperative blood loss, postoperative hospital stay, postoperative gastrointestinal decompression time and postoperative closed drainage time in all patients were significantly less than those in the control group (P <0.05). The incidence of reflux esophagitis, gastric emptying disorder, thoraco-gastric syndrome, anastomotic stenosis and anastomotic fistula in the treatment group were significantly less than those in the control group (P <0.05) 3 months after surgery The status, treatment-related symptoms, social effects, emotional activity scores were significantly higher than the control group (P <0.05). Conclusion: Compared with total esophageal esophagectomy, the use of tubular esophageal esophageal esophageal esophageal cancer in the treatment of esophageal cancer patients with better safety and effectiveness, it is worth further clinical research and promotion.