论文部分内容阅读
发生在高加索人的慢性淋巴细胞性白血病(CLL)几乎总是由于具有圆形核的小B淋巴细胞增生而很少累及皮肤。只有极少数CLL病例,其增生细胞来源于T细胞。这样的CLL病人,增生的T细胞也有一个圆核,在胞浆中似乎有许多嗜苯胺蓝颗粒。这种CLL象其他慢性T淋巴细胞增生紊乱性疾病一样,很容易侵犯皮肤。目前可以使用单克隆抗体确定T细胞的表型,从而将其分成不同的亚群。T3是所有的T淋巴细胞标志,T 4细胞标志与辅助性细胞有关,T8为抑制性/胞毒性细胞的标志。恶性T淋巴细胞常常
Chronic lymphocytic leukemia (CLL) in Caucasians occurs almost invariably due to the proliferation of small B lymphocytes with round nuclei with little involvement of the skin. Only a very small number of CLL cases, the proliferation of cells derived from T cells. In such CLL patients, the proliferating T cells also have a round nucleus that appears to have many azote-azurin granules in the cytoplasm. Like other chronic T-cell proliferative disorders, this CLL can easily invade the skin. Monoclonal antibodies are currently available to determine the phenotype of T cells, dividing them into distinct subsets. T3 is all T lymphocyte markers, T 4 cell markers and helper cells, T8 is a marker of inhibitory / cytotoxic cells. Malignant T lymphocytes often