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前淋巴细胞白血病(简称PL)是一种新近报告的少见的白血病。目前国内外报道不多。我室最近遇到一例,对其进行了病变组织常规HE检查、酶组织化学、免疫学及电镜检查,现报告如下。患者男性,56岁,因消瘦、乏力、多汗,左上腹包块进行性增大三个月就诊。检查:全身表浅淋巴结轻度肿大,直径约0.5～0.8cm,脾巨大,A线16cm,B线20cm,C线8cm,可扪及脾切迹,表面光滑。胸骨柄轻度压痛。Hb11.5g,WBC32000,N6％,L94％,TC4.6万。临床以“慢性淋巴细胞性白血病”收住院。入院后行预淋巴结摘除并进行病理检查。骨髓及血涂片均显示淋巴系统增生,前淋巴细胞占30～50％,故行脾切除。将颈淋巴结及脾脏切除的标本处理后行组织学、酶组织化学,免疫学及电镜检查。
Pre-lymphocytic leukemia (PL) is a newly reported rare leukemia. At present, few reports at home and abroad. My room recently encountered a case of its routine lesions HE examination, enzyme histochemistry, immunology and electron microscopy, are as follows. Male patient, 56 years old, due to weight loss, fatigue, sweating, left upper abdominal mass progressively increased three months treatment. Check: The whole body superficial lymph nodes slightly enlarged, diameter of about 0.5 ~ 0.8cm, splenomegaly, A line 16cm, B line 20cm, C line 8cm, palpable and splenic notch, smooth surface. Slight mild tenderness of the sternum. Hb11.5g, WBC32000, N6%, L94%, TC4.6 million. Clinical “chronic lymphocytic leukemia” admitted to hospital. After admission, pre-lymph node removal and pathological examination. Bone marrow and blood smears showed lymphoid hyperplasia, pre-lymphocytes accounted for 30 to 50%, so the line splenectomy. The cervical lymph nodes and splenectomy specimens after treatment line histochemistry, enzyme histochemistry, immunology and electron microscopy.