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目的:探讨急性有机磷农药中毒(AOPIP)患者死亡的相关因素。方法:收治急性有机磷农药中毒患者70例,回顾性分析其临床资料。结果:使用呼吸机的优势比{Exp(B)}=40.177、Wald=6.418、P=0.011,差异有统计学意义,也就是说使用呼吸机患者的死亡率为不用呼吸机患者的40余倍。是否做血液灌流的优势比{Exp(B)}=0.007、Wald=6.495、P=0.011,差异有统计学意义。胆碱酯酶水平优势比{Exp(B)}=0.996、Wald=4.922、P=0.027,差异有统计学意义;死亡组的胆碱酯酶水平(437.538 5±519.983 75)U/L,存活组(1 541.052 6±1 076.994 22)U/L。19例执行血液灌流患者的死亡结果差异无统计学意义。结论:急性有机磷农药患者使用呼吸机的死亡率高,使用血液灌流的死亡率低,胆碱酯酶水平较低的死亡率高。
Objective: To investigate the related factors of death in acute organophosphorus pesticide poisoning (AOPIP) patients. Methods: 70 cases of acute organophosphorus pesticide poisoning patients, retrospective analysis of its clinical data. Results: The advantage of using ventilator was {Exp (B)} = 40.177, Wald = 6.418, P = 0.011, the difference was statistically significant, that is to say, the death rate of ventilator patients was more than 40 times . The advantage of hemoperfusion than {Exp (B)} = 0.007, Wald = 6.495, P = 0.011, the difference was statistically significant. The ratio of cholinesterase in the death group was (437.538 5 ± 519.983 75) U / L, which was higher than {Exp (B)} = 0.996, Wald = 4.922, P = 0.027, the difference was statistically significant Group (1 541.052 6 ± 1 076.994 22) U / L. No significant difference was found in the mortality of 19 patients who underwent hemoperfusion. CONCLUSIONS: Acute organophosphorus pesticide use in patients with ventilator mortality is high, the use of hemoperfusion mortality is low, cholinesterase lower mortality.