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作者报告一例单侧腓肠肌真性肥大。认为骨骼肌真性肥大系失神经性病理变化。 47岁,男性,4年前发现左侧腓肠肌单侧性肥大。其双亲为表兄妹。检查所见左侧腓肠肌最大周径比右侧大6 cm。右踝反射消失。右侧腓肠肌萎缩。颈、胸、腰椎x光照片及脊髓造影检查均未发现异常。两侧腓肠肌、胫前肌、股四头肌、腘绳肌肌电图显示4～9mv的高幅电位。时限8～12ms和减弱的干扰相。左侧腓肠肌动作电位减少。双上肢肌电图和四肢运动神经传导速度正常。左腓肠肌活检示肌纤维增粗,平均直径86.5μm,最大直径达140μm,而脂肪结缔组织无增生。部分细胞核浓缩变形,可见少量角状纤维,肌纤维和细胞核崩解。右侧腓肠
The authors report a case of unilateral gastrocnemius true hypertrophy. Skeletal muscle that real hypertrophy Department of neurological pathology. 47 years old, male, unilateral hypertrophy of the left calf muscle found 4 years ago. Their parents are cousins. Examination showed that the left gastrocnemius muscle maximum circumference than the right 6 cm. Right ankle reflex disappeared. Right gastrocnemius atrophy. Neck, chest, lumbar x-ray and myelography were not found abnormalities. On both sides of the gastrocnemius, anterior tibialis, quadriceps, hamstrings EMG showed high amplitude of 4 ~ 9mv. Time 8 ~ 12ms and weakened the phase of interference. Left gastrocnemius action potential decreased. Both upper extremity EMG and limb motor nerve conduction velocity was normal. Left gastrocnemius muscle biopsy showed muscle fiber thickening, the average diameter of 86.5μm, the maximum diameter of 140μm, while adipose connective tissue without proliferation. Part of the nucleus concentrated deformation, showing a small amount of horny fibers, muscle fibers and nucleus collapse. Right sural