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肥胖是目前非酒精性脂肪性肝病(NAFLD)的常见原因,在全球其发病率近年来随着肥胖的盛行而迅猛增长。NAFLD与代谢综合征(MS)和胰岛素抵抗的关系密切。体重上升,尤其是腹腔内脂肪的增加是NAFLD和MS发生和进展的高危风险。对于肥胖相关的NAFLD患者,减肥是惟一有效的治疗方法,合理控制饮食,增加有氧运动,建立良好的心理行为是防治NAFLD的关键;目前还缺乏有关设计良好的药物和手术对肥胖相关的NAFLD的对照研究结论。
Obesity is a common cause of current non-alcoholic fatty liver disease (NAFLD) and its morbidity in the world has increased rapidly with the prevalence of obesity in recent years. NAFLD and metabolic syndrome (MS) and insulin resistance are closely related. Weight gain, especially intraperitoneal fat, is a high-risk risk for the onset and progression of NAFLD and MS. To obesity-related NAFLD patients, weight loss is the only effective treatment, reasonable diet, increase aerobic exercise, establish good psychological behavior is the key to prevention and treatment of NAFLD; currently there is a lack of well-designed drugs and surgery for obesity-related NAFLD The control study concluded.