氯原酸是一种广泛存在于植物性食物和咖啡饮品中的酚酸。研究表明它具有多种有益人体健康的生物活性。近来它调节糖脂代谢、增强胰岛素敏感性的生物活性受到人们的关注,这为通过饮食防治肥胖、糖尿病等慢性疾病提供科学的依据。本文就氯原酸与糖脂代谢的研究进展及其机制进行综述。 Chlorogenic acid is a phenolic acid widely found in plant foods and coffee drinks. Research shows that it has a variety of biological activity beneficial to human health. Recently, it regulates the metabolism of glucose and lipid and enhances the biological activity of insulin sensitivity by people’s attention, which provides a scientific basis for the prevention and treatment of chronic diseases such as obesity and diabetes through diet. This article reviews the progress and mechanism of chlorogenic acid and glycolipid metabolism.