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目的观察通塞脉片治疗脑梗死并发下肢深静脉血栓形成的临床疗效。方法将53例脑梗死并发下肢深静脉血栓形成患者随机分为两组;治疗组29例给予通塞脉片联合尿激酶、低分子肝素治疗,对照组24例仅给予尿激酶、低分子肝素治疗。两组疗程均为14天;采用彩色多普勒超声检测患肢静脉血管再通情况以评估临床疗效,并检测治疗前后血液流变学变化。结果治疗后治疗组的临床疗效优于对照组(P<0.05);两组治疗后血液流变学指标均有不同程度改善(P<0.05),且治疗组改善明显优于对照组(P<0.05)。结论通塞脉片结合西医常规疗法治疗脑梗死并发下肢深静脉血栓形成疗效确切。
Objective To observe the clinical curative effect of Tongsaimai tablet on cerebral infarction complicated with deep venous thrombosis of lower extremities. Methods 53 cases of cerebral infarction complicated by deep venous thrombosis of lower extremities were randomly divided into two groups; the treatment group, 29 cases were given Tongsaimailian combined with urokinase and low molecular weight heparin; the control group, 24 cases, only given urokinase and low molecular weight heparin . Both groups were treated for 14 days; color Doppler ultrasound detection of limb vein recanalization to assess clinical efficacy, and to detect changes in hemorheology before and after treatment. Results After treatment, the clinical efficacy of the treatment group was better than that of the control group (P <0.05). The indexes of hemorheology in both groups were improved to some extent (P <0.05), and the improvement in the treatment group was obviously better than that in the control group (P < 0.05). Conclusion Tongsai tablets combined with Western conventional therapy for the treatment of cerebral infarction complicated by deep venous thrombosis lower extremity curative effect.