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报道了用抗人肝癌单克隆抗体(McAb)制备的HAg18-1血清快速EIA检测试剂对良恶性消化系疾病血清检测结果。阳性率如下:原发性肝癌(PLC)79.63％(43/54);肝硬变9.09％(2/22);乙型肝炎4.88％(2/41);胃癌23.08％(6/26);大肠癌20％(5/25)。19例胃肠炎、16名正常人均为阴性。该试剂对PLC诊断的特异性为89.52％,HAg18-1阳性与甲胎蛋白(AFP)含量无关。两者合用对PLC诊断阳性率达94.44％。
The results of serum detection of benign and malignant digestive diseases using HAg18-1 serum rapid EIA reagent prepared with anti-human hepatoma monoclonal antibody (McAb) were reported. The positive rates were as follows: 79.63% (43/54) of primary liver cancer (PLC); 9.09% (2/22) of cirrhosis; 4.88% (2/41) of hepatitis B; 23.08% (6/26) of gastric cancer; Colorectal cancer 20% (5/25). 19 cases of gastroenteritis and 16 normal persons were all negative. The specificity of this reagent for the diagnosis of PLC was 89.52%. HAg18-1 positive was not associated with alpha fetoprotein (AFP) content. The positive rate of the combination of the two for PLC diagnosis was 94.44%.