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目的 :探讨非甾体类抗炎药物酮咯酸氨丁三醇 (ketorolacTromethamine)对兔眼准分子激光角膜切削术(PRK)后角膜雾状混浊 (haza)的作用效果。方法 :将已行PRK术的 2 4只兔眼随机分配到A、B、C 3组 ,每组 8只眼。术后A组点 0 .1%地塞米松液 ,B组点 0 .5 %酮咯酸氨丁三醇眼液 ,C组作为空白对照。剂量为 :第 1月 4次/d ,第 2月 3次 /d。术后 1周、1月、2月时检查haze情况。结果 :术后 1周时 ,3组之间haze的差异均无显著性。术后 1月及 2月时 ,A组、B组的haze较C组轻 ,A组、B组之间的差异则无显著性。结论 :酮咯酸氨丁三醇对兔眼PRK术后的haze有抑制作用。
Objective: To investigate the effect of ketorolacTromethamine, a non-steroidal anti-inflammatory drug, on haza after corneal ophthalmic keratotomy (PRK). Methods: Twenty-four eyes of PRK group were randomly assigned to A, B and C groups, with 8 eyes in each group. Postoperative A group of 0.1% dexamethasone, B group point 0.5% ketorolac tromethamine eye drops, C group as a blank control. Doses were: 4 times in January / d, 3 times in February / d. After 1 week, January, February check haze situation. Results: There was no significant difference in haze between the three groups at 1 week after operation. At 1 month and 2 months after operation, the haze in group A and group B was lighter than that in group C, and the difference between group A and group B was not significant. Conclusion: Ketorolac tromethamine inhibits haze after PRK in rabbit eyes.