This paper proposed an optimized fast handoff scheme for real-time applications in next generation IPbased CDMA wireless networks. The idea is to utilize optimized IP multicasting handoff (based on PIM-SM),which is triggered by CDMA layer-2 functionality. An IP-based cellular network model with WCDMA FDD air interface and IP-based packet traffic is adopted. No special network entities and signaling for handoff are added in our network model. The simulation results show that low delay and low packet-lost-rate can be obtained.