静脉滴注抗生素,是临床治疗危重感染病人的一项主要措施。根据已知抗生素的有关药理参数,可对各种药物的体内过程,进行定量比较。并可依所得参数来制定合理的给药方案,预测毒性反应的发生而及时采取预防措施。现就应用药物动力学中,静滴药物血药浓度与时间的关系式,按叠合原理,预测计算出常用抗生素各种给药方案的血药浓度。 Intravenous infusion of antibiotics, clinical treatment of critically ill patients is a major measure. According to the known pharmacological parameters of antibiotics, the in vivo process of various drugs can be compared quantitatively. And according to the parameters to formulate a reasonable dosing regimen to predict the occurrence of toxic reactions and take timely preventive measures. Now on the application of pharmacokinetics, intravenous drug blood concentration and time relationship, according to the principle of overlap, predict the calculation of the commonly used antibiotics various drug regimens of blood concentration.