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目的分析并了解肾脏疾病患者肾组织病理类型的分布。方法对我院2010年1月至2012年12月间肾脏疾病患者150例肾活检病理资料进行回顾性分析。结果①150例肾脏疾病患者中原发性肾小球疾病104例,占69.33%;继发性肾小球疾病31例,占20.67%。②原发性肾小球疾病病理分型中最常见系膜增生性肾小球肾炎(47.12%),其次为IgA肾病(17.31%)及局灶节段肾小球硬化症(12.50%),微小病变占10.58%。③继发性肾小球疾病中狼疮性肾炎居于首位(45.16%),其次为紫癜性肾炎(22.58%);继发性肾小球疾病病理类型最常见局灶节段硬化性肾炎(32.26%),其次为系膜增生性肾炎(22.57%)。结论目前原发性肾小球肾炎仍为最常见及主要的肾小球疾病,其中最常见病理类型为系膜增生性肾炎。肾脏疾病临床表现与病变程度往往不相一致,因此肾活检病理对临床明确诊断,指导治疗方案及评估患者的预后有重要意义。
Objective To analyze and understand the distribution of renal histopathological types in patients with kidney disease. Methods Retrospective analysis of 150 cases of renal biopsy in our hospital from January 2010 to December 2012 were retrospectively analyzed. Results ① Among the 150 cases of kidney diseases, 104 were primary glomerular diseases, accounting for 69.33%. Secondary glomerular diseases were 31 cases, accounting for 20.67%. ② The most common pathological types of primary glomerular mesangial proliferative glomerulonephritis (47.12%), followed by IgA nephropathy (17.31%) and focal segmental glomerulosclerosis (12.50%), Minor lesions accounted for 10.58%. ③ In the secondary glomerular disease, lupus nephritis was the first (45.16%), followed by purpura nephritis (22.58%). The pathological type of secondary glomerular disease was the most common focal sclerosis (32.26% ), Followed by mesangial proliferative glomerulonephritis (22.57%). Conclusion At present, primary glomerulonephritis is still the most common and major glomerular disease. The most common pathological type is mesangial proliferative glomerulonephritis. The clinical manifestations of renal disease and the degree of lesions are often not consistent, so the pathological renal biopsy for clinical diagnosis, guiding treatment programs and assess the prognosis of patients with great significance.