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肾衰时由于机体抵抗力低下容易并发各种感染,感染又是使肾功能进一步恶化和致死的主要原因,但感染是一个可逆因素,诊断和抢救及时、处理得当,可使大多数患者转危为安。 肾衰并发感染的治疗方法同样包括全身支持疗法和特殊治疗等,不同的是在对肾功能不全患者选择和使用抗生素时,医生不仅需要了解抗生素的抗菌谱还需掌握肾功不全时调整给药方案的方法。这是因为许多抗生素经肾排泄,肾功不全时药物排出减少,如按常规用量给药,休内药物将蓄积甚至达中毒水平。因此,必须根据肾衰程度调整给药方案才能使治疗取得最佳效果而不致中毒。
Renal failure due to low body resistance easily complicated by a variety of infections, the infection is to further deteriorate renal function and death of the main reason, but the infection is a reversible factor, timely diagnosis and rescue, properly handled, most patients can turn theback. Treatment of renal failure complicated by infection also includes systemic supportive therapy and special treatment, the difference is that in the selection and use of antibiotics in patients with renal insufficiency, the doctor not only need to understand the antimicrobial antibiotics spectrum also need to master the adjustment of renal insufficiency Program approach. This is because many antibiotics excreted by the kidneys, renal insufficiency decreased drug excretion, such as conventional dosage, off drug will accumulate or even up to the level of poisoning. Therefore, we must adjust the dosage according to the degree of renal failure in order to make the best treatment without toxic effects.