本文研究了VCN与MMC、5-Fu合用及单用MMC、5-Fu处理S_(180)瘤苗对小鼠进行免疫后给予S_(180)细胞攻击,观察其免疫保护效应。分析VCN对肿瘤细胞及在瘤苗免疫中的作用。实验结果表明。各组瘤苗均能使小鼠对S_(180)细胞的攻击产生一定的抵抗力。VCN+5Fu和VCN+MMC所制成的瘤苗,抑瘤效果最好,抑瘤率分别达到95.22％及94.20％。 In this study, we investigated the effects of VCN and MMC, 5-Fu in combination with MMC and 5-Fu alone on immunization of mice immunized with S 180 tumor vaccine. The effect of VCN on tumor cells and in tumor vaccine immunity was analyzed. Experimental results show. Each group of tumor vaccines can make mice have a certain resistance to the attack of S_(180) cells. The tumor vaccines made by VCN+5Fu and VCN+MMC had the best anti-tumor effect, and the tumor inhibition rates were 95.22% and 94.20%, respectively.