我科自1980至1985年末用液氮冷冻治疗耳廓及外鼻皮肤癌30例,经较长时间随访,疗效满意,报告如下。 一、动物实验 冷冻杀死肿瘤全部癌细胞,要求瘤体底部达到-20℃～-30℃,维持1分钟以上。为测试我科改装的电动加压液氮冷冻治疗器的降温性能,摸索冷冻治疗耳廓及外鼻皮肤癌的有效剂量,测试皮下0.5cm组 In our department, from the end of 1980 to the end of 1985, 30 cases of auricle and external nose skin cancer were treated with liquid nitrogen. After a long period of follow-up, the results were satisfactory. The report is as follows. First, animal experiments Frozen to kill all tumor cells, require the bottom of the tumor to reach -20 °C ~ -30 °C, maintain more than 1 minute. To test the cooling performance of our electric modified liquid nitrogen cryotherapy device, to explore the effective dose of cryotherapy for auricle and external nose skin cancer, to test the subcutaneous 0.5cm group