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目的探讨胎儿脉络丛囊肿的产前诊断和临床意义。方法观察2003年1月～2007年1月在本院产前超声检查发现的胎儿脉络丛囊肿,分析胎儿超声改变与染色体的关系和预后。结果共发现胎儿脉络丛囊肿56例。46例为单侧囊肿,10例为双侧囊肿。45例胎儿脉络丛囊肿于晚孕前消失,在本院足月分娩,新生儿无异常发现;8例中期引产;3例失访。16例行羊水穿刺,6例胎儿染色体异常(其中3例为18-三体染色体异常)。结论胎儿脉络丛囊肿发生率为0.96%,其与染色体异常密切相关;当囊肿直径在0.5～1cm之间,如发现胎儿染色体异常的超声标记或合并有胎儿解剖结构异常建议行胎儿染色体核型分析;囊肿大于1cm建议行胎儿染色体核型分析。
Objective To investigate the prenatal diagnosis and clinical significance of fetal choroid plexus cysts. Methods Fetal choroid plexus was observed in prenatal ultrasound examination in our hospital from January 2003 to January 2007, and the relationship and prognosis of fetal choroidal echocardiography were analyzed. Results A total of 56 cases of fetal choroid cyst were found. 46 cases of unilateral cyst, 10 cases of bilateral cysts. 45 cases of fetal choroid plexus cyst disappeared before the first trimester, in our hospital full-term delivery, no abnormalities were found in the newborn; 8 cases of induced abortion; 3 cases were lost. 16 cases of amniocentesis, 6 cases of fetal chromosomal abnormalities (including 3 cases of 18-trisomy chromosome abnormalities). Conclusions The incidence of fetal choroid plexus cyst is 0.96%, which is closely related to chromosomal abnormalities. When cyst diameter is between 0.5cm and 1cm, fetal chromosomal karyotype analysis is suggested if ultrasound signs of fetal chromosomal abnormalities or fetal anatomy abnormalities are found Cysts greater than 1cm recommended line fetal karyotype analysis.