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目的分析舟山海岛地区育龄妇女婚前、孕前弓形虫、风疹病毒、巨细胞病毒、单纯疱疹病毒即TORCH的检测结果,探讨其临床意义。方法采用ELISA法检测普陀区2009年7月-2013年6月进行婚检的育龄妇女血清中TORCH各项特异性Ig M和Ig G抗体。婚检若是Ig M阳性,建议其近期不要怀孕,若R-Ig G阴性的妇女则提供免费疫苗接种。结果 1 523例婚检妇女中,检测出Ig M阳性的妇女,经合理指导,避开高风险期,在孕期呈显著降低或已经愈合检测不到。对R-Ig G阴性的妇女给予风疹疫苗接种后都具有了Ig G抗体,有效降低了风疹病毒感染。结论舟山海岛地区TORCH-Ig M阳性率较低,在孕前接受TORCH检测,排除病原体感染,可有效提高优生率。
Objective To analyze the detection of Toxoplasma gondii, rubella virus, cytomegalovirus and herpes simplex virus (TORCH) in pre-marital and pre-pregnancy women of childbearing age in Zhoushan Island, and to explore its clinical significance. Methods TORCH specific Ig M and Ig G antibodies in sera from women of childbearing age who passed the premarital examination from July 2009 to June 2013 in Putuo District were detected by ELISA. If pre-marital immunoglobulin Ig M is positive, it is recommended not to be pregnant in the near future, and to provide free vaccination if R-Ig G negative women. Results Among the 1 523 premarital women, IgM-positive women detected with reasonable guidance avoided the high-risk period and had significantly decreased or recovered during pregnancy. Rubella vaccination with Ig G antibodies to women with R-Ig G negative results in an effective reduction of rubella virus infection. Conclusion The positive rate of TORCH-Ig M in Zhoushan island area is low. TORCH was detected before pregnancy and pathogen infection was excluded, which can effectively improve the rate of eugenics.