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目的探讨糖尿病并发心肌梗死患者超敏C反应蛋白(hs-CRP)与致动脉硬化指数(AIP)相关性及其临床意义。方法选取52例糖尿病并发心肌梗死患者,检测各患者血浆hs-CRP、HbAlc、CHO、TG、HDL-C、LDL-C等水平,计算致动脉硬化指数;选取60例糖尿病无心肌梗死患者作为对照组。结果糖尿病并发心肌梗死患者血浆hs-CRP、AIP明显高于对照组,并且无论是糖尿病并发心肌梗死还是对照组,hs-CRP水平与AIP无相关性。结论 hs-CRP与心肌梗死的发生有密切关系,可能是独立于TG、HDL-C、LDL-C以外的糖尿病并发心肌梗死相关危险因素。AIP与糖尿病并发心肌梗死有关。
Objective To investigate the correlation between hs-CRP and arteriosclerosis index (AIP) in patients with diabetes complicated with myocardial infarction and its clinical significance. Methods Fifty-two patients with diabetes mellitus complicated with myocardial infarction were selected to detect the levels of hs-CRP, HbA1c, CHO, TG, HDL-C and LDL-C in each patient and calculate the index of atherothrombosis. Sixty patients with diabetes mellitus without myocardial infarction group. Results The plasma levels of hs-CRP and AIP in patients with diabetes mellitus complicated with myocardial infarction were significantly higher than those in the control group. There was no correlation between hs-CRP and AIP in both diabetic and myocardial infarction patients. Conclusion hs-CRP is closely related to the occurrence of myocardial infarction and may be a risk factor for diabetes mellitus complicated with myocardial infarction independent of TG, HDL-C and LDL-C. AIP and diabetes complicated with myocardial infarction.