论文部分内容阅读
目的通过对新疆汉族和维吾尔族老年冠心病患者经皮冠状动脉介入治疗(PCI)时靶病变冠状动脉钙化检测及干预结果比较,探讨介入治疗中不同民族老年冠心病患者冠状动脉粥样硬化斑块钙化(CAC)检出率是否存在差异及其临床意义。方法回顾性分析我院2005年1月至2006年12月成功接受PCI的汉族和维吾尔族老年(年龄≥60岁)冠心病患者的冠状动脉造影结果,PCI并发症等临床资料。结果545例汉族和维吾尔族老年冠心病患者CAC总检出率为37.6%。其中维吾尔族患者CAC的检出率为49.3%,明显高于汉族患者29.8%(P<0.05),维吾尔族男性患者CAC的检出率明显高于汉族男性患者(55.3%比35.0%,P<0.05),而女性患者两组间差异无统计学意义(22.5%比19.2%,P>0.05)。维吾尔族患者术中冠状动脉夹层发生率明显高于汉族患者(37.8%比19.3%,P<0.05)。亚组分析,维吾尔族患者中91.8%冠状动脉夹层发生于靶血管病变CAC患者,略高于汉族患者(82.7%),但差异无统计学意义(P>0.05)。PCI术中慢血流发生率维吾尔族患者较汉族患者高(28.7%比9.3%,P<0.05);而支架内急性血栓发生率,两组间差异无统计学意义。结论新疆汉族和维吾尔族老年冠心病患者冠状动脉钙化发生率存在差异,致使维吾尔族患者PCI术中冠状动脉夹层和慢血流的发生率明显高于汉族患者。因此对维吾尔族患者应选择恰当的技术和方法减少术中冠状动脉夹层和慢血流的发生。
Objective To investigate the coronary artery calcification in the elderly patients with coronary heart disease (PCI) in Han and Uygur nationality in Xinjiang and to compare the intervention results to explore the interventional treatment of coronary heart disease in different ethnic elderly patients with coronary atherosclerotic plaque Whether the detection rate of calcification (CAC) is different and its clinical significance. Methods The clinical data of coronary angiography, PCI complications and other clinical data were retrospectively analyzed in our hospital from January 2005 to December 2006 in Han and Uighur elderly patients (aged ≥60 years) with coronary heart disease. Results The total positive rate of CAC in 545 Han and Uighur elderly patients with coronary heart disease was 37.6%. Among them, the detection rate of CAC in Uighur patients was 49.3%, significantly higher than that in Han patients (29.8%, P <0.05). The detection rate of CAC in Uygur male patients was significantly higher than that in Han male patients (55.3% vs 35.0%, P < 0.05). There was no significant difference between the two groups in female patients (22.5% vs 19.2%, P> 0.05). The incidence of coronary artery dissection in Uighur patients was significantly higher than that in Han patients (37.8% vs. 19.3%, P <0.05). In the subgroup analysis, 91.8% of coronary artery dissections in Uygur patients occurred in CAC patients with target vascular lesions, slightly higher than in Han patients (82.7%), but the difference was not statistically significant (P> 0.05). The incidence of slow blood flow in PCI patients was higher than that in Han patients (28.7% vs 9.3%, P <0.05). The incidence of acute thrombosis within the stent was not significantly different between the two groups. Conclusions The prevalence of coronary artery calcification in elderly Han and Uighur elderly patients with coronary heart disease in Xinjiang is different. The incidence of coronary artery dissection and slow blood flow in Uygur patients is significantly higher than that in Han patients. Therefore, Uighur patients should choose the appropriate techniques and methods to reduce the incidence of intraoperative coronary artery dissection and slow blood flow.